Bicara Therapeutics
Bicara Therapeutics is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara's lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR) directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-β). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF-β signaling within the tumor microenvironment. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types. The company values building diverse teams and cultivating an inclusive culture, encouraging applications from all backgrounds.
Bicara Therapeutics values building diverse teams and cultivating an inclusive culture where all voices are included. The company encourages applications from people of all backgrounds and is committed to equal opportunity employment.
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Website
bicara.com
Company Size
51-100 employees
Location
Boston, MA
Industry
Pharmaceutical and Medicine Manufacturing
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