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HEOR Analytics CoE Senior Manager

Vertex Pharmaceuticals

Boston, MA
Full Time
Senior
136k-204k
about 23 hours ago

Job Description

About the Role

Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The role is as a Senior Manager within HEOR's Modeling & Analytics Center of Excellence (CoE), a designated group within the HEOR team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization. The main responsibility of the Senior Manager will be to support the HEOR disease/asset teams in real-world observational and claims data research activities, leveraging Vertex's in-licensed RWE data assets to answer questions related to disease prevalence, burden, healthcare resource utilization, costs, and treatment patterns in 'real world' populations.

Key Responsibilities

  • Leverage Vertex's in-licensed RWE data assets to conduct queries and analyses to support the Vertex product portfolio and development therapeutic and disease areas.
  • Conduct feasibility assessments to inform research projects.
  • Conduct health economic and outcome studies to better characterize disease burden, healthcare resource utilization, co-morbidities, and treatment patterns in 'real world' populations.
  • Generate insights to inform key business questions raised by internal and external stakeholders.
  • Support development of protocols and statistical analysis plans, including table shells and code compilation.
  • Support statistical programmers through execution of data queries and analyses.
  • Generate analytic reports, tables, and graphics to communicate research findings and present to internal stakeholders.
  • Collaborate with cross-functional colleagues to improve efficiency of current analytic operating model.
  • Contribute to program library and analytic tools development (e.g., reusable macros, programming templates) and maintenance to ensure quality of data and analyses.
  • Support HEOR disease/asset leads in assessment of research gaps and objectives that may be supported by observational research.

Requirements

  • Advanced degree in health economics or a related discipline (such as mathematics, statistics, economics, epidemiology).
  • Typically requires 6 years of relevant experience in health economics and outcomes research, or the equivalent combination of education and experience.
  • Experience analyzing large patient-level data and conducting statistical analyses within health databases, including open and closed claims, EHR/EMR data, and hospital chargemaster data (e.g., MarketScan, Premier, DRG).
  • Working knowledge of relevant national healthcare systems; experienced with diagnostic, procedure, drug, and healthcare coding systems.
  • Advanced skills with SAS programming and Excel required.
  • Excellent communication skills, strong oral/written presentation skills.
  • Ability to plan, organize, and work on multiple tasks simultaneously in different therapeutic areas.
  • Ability to navigate and be successful in a fast-paced, dynamic team-based environment.

Nice to Have

  • Experience with global product value strategy and tactics.
  • Experience with designing and interpreting post-hoc clinical trial analyses and evidence generation studies.

Qualifications

  • Advanced degree in health economics or a related discipline.

Benefits & Perks

  • Eligible for an annual bonus and annual equity awards.
  • Total Rewards offerings include medical, dental, and vision benefits.
  • Generous paid time off, including a week-long company shutdown in Summer and Winter.
  • Educational assistance programs including student loan repayment.
  • Commuting subsidy, matching charitable donations, 401(k), and more.

Working at Vertex Pharmaceuticals

Vertex is a global biotechnology company that invests in scientific innovation. The company is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants, with accommodations for individuals with disabilities. It fosters a diverse, inclusive, and innovative work environment.

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Job Details

Posted AtAug 6, 2025
Job CategoryData Analytics
Salary136k-204k
Job TypeFull Time
Work ModeHybrid
ExperienceSenior

Job Skills

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About Vertex Pharmaceuticals

Website

vrtx.com

Company Size

5001-10000 employees

Location

Boston, MA

Industry

Pharmaceutical and Medicine Manufacturing

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