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Product Director, Oncology

Guardant Health

Palo Alto, CA
Full Time
Director
183k-251k
16 days ago

Job Description

About the Role

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. The Guardant Health Product Director, Oncology, reports to the Senior Director of Product Management. This role will be a product management focused role responsible for driving market evolution in one of Guardant Health's leading oncology products. This is a pivotal role for a strategic and execution-driven leader who thrives at the intersection of product innovation, clinical impact, and commercial growth. The Product Director, Oncology will lead the product strategy, roadmap execution, and commercial readiness for one of Guardant's most strategic offerings. This role will have the opportunity to shape how a high-impact diagnostic enters standard of care and influence how to accelerate adoption in a growing MRD market and will work closely with technical, clinical, medical, and commercial teams to drive product's value proposition, evidence strategy, and product-market fit across indications.

Key Responsibilities

  • Lead end-to-end execution of the designated product roadmap including new features, workflow enhancements, and indication expansion.
  • Serve as the subject matter expert in the field and drive future concepts for product development.
  • Drive product launch execution through phase gates, commercial excellence programs and drive overall product readiness initiatives.
  • Translate strategic goals into executable plans with clear timelines, KPIs, and milestones tied to business outcomes.
  • Work cross-functionally with R&D, clinical development, regulatory, and commercial to drive product delivery from concept to launch.
  • Identify and resolve executional risks to ensure timely and successful product development and rollout.
  • Engage directly and through sales/marketing teams with oncologists, NPs, practice managers, and IDNs to understand MRD use cases and pain points.
  • Engage with external BioPharma customers to navigate their MRD product needs, requirements and workflow.
  • Define and prioritize product capabilities that align with clinical workflows and improve user experience.
  • Ensure the product aligns with both physician needs and payer expectations, including actionable results and clinical utility.
  • Own the business case for one of Guardant Health's leading products, including pricing, COGS, and contribution to the overall oncology portfolio.
  • Monitor competitive activity in MRD and adjacent markets, and shape Guardant Health's product market differentiation strategy accordingly.
  • Partner with Market Access and Medical Affairs teams to ensure the evidence plan supports reimbursement and payer acceptance.
  • Collaborate with Sales and Marketing teams to help drive positioning, messaging, and launch strategies.
  • Support development of customer-facing materials, sales training, and field enablement to drive adoption and growth.
  • Contribute to publication planning and scientific communications that support the product's value proposition across tumor types.

Requirements

  • Typically requires a university degree and typically 15 years of related experience; or 12 years and a Master's degree; or 8 years and a PhD; or 5 years and a PharmD/MD.
  • Bachelor's degree required; MBA, MPH, or advanced scientific degree preferred.
  • 8+ years of product management or commercial/medical affairs strategy experience in diagnostics, oncology, or health technology.
  • Demonstrated success in launching and scaling healthcare products in the oncology or molecular diagnostics space.
  • Deep understanding of MRD (Minimal Residual Disease), liquid biopsy, or cancer surveillance markets.
  • Strong working knowledge of patient and oncologist journey/touch points in the MRD space.
  • Comprehensive knowledge of MRD competitive landscape, offerings across diagnostic providers, and reimbursement strategies.
  • Strong strategic thinking, execution rigor, and cross-functional leadership skills.
  • Prior experience with product development, lifecycle management, and product launch.
  • Commercial awareness with understanding of market access, evidence generation, and provider adoption drivers.

Nice to Have

  • Experience with product development, lifecycle management, and product launch experience.
  • Knowledge of the reimbursement landscape and evidence strategies.
  • Experience working with external BioPharma customers.

Qualifications

  • Bachelor's degree required.
  • Typically 15 years of related experience, or 12 years with a Master's, or 8 years with a PhD, or 5 years with a PharmD/MD.

Benefits & Perks

  • Pay transparency with a base salary range of $182,700 to $251,250 for positions in Palo Alto, CA or Redwood City, CA.
  • Work model includes defined in-office days and work-from-home days to support work-life balance.
  • Potential bonus, commission, or equity (not included in base salary range).
  • Reasonable accommodations for candidates with disabilities or other conditions.

Working at Guardant Health

Guardant Health is committed to diversity and equal opportunity employment, providing reasonable accommodations, and fostering an inclusive environment. The company emphasizes collaboration, innovation, and a focus on advancing science for patients.

Apply Now

Job Details

Posted AtJul 10, 2025
Job CategoryProduct Management
Salary183k-251k
Job TypeFull Time
Work ModeHybrid
ExperienceDirector

Job Skills

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About Guardant Health

Website

guardanthealth.com

Company Size

1001-5000 employees

Location

Palo Alto, CA

Industry

Medical and Diagnostic Laboratories

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