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Product Director, Oncology

Guardant Health

Palo Alto, CA
Full Time
Director
183k-251k
30 days ago

Job Description

About the Role

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. The company’s tests help improve outcomes across all stages of care, including screening, monitoring for recurrence, and treatment selection for patients with cancer. The Product Director, Oncology, reports to the Senior Director of Product Management and is responsible for driving market evolution in one of Guardant Health's leading oncology products, shaping how diagnostic tools enter standard of care and influencing adoption in the MRD market.

Key Responsibilities

  • Lead end-to-end execution of the designated product roadmap, including new features, workflow enhancements, and indication expansion.
  • Serve as the subject matter expert in the field and drive future concepts for product development.
  • Drive product launch execution through phase gates, commercial excellence programs, and overall product readiness initiatives.
  • Translate strategic goals into executable plans with clear timelines, KPIs, and milestones tied to business outcomes.
  • Work cross-functionally with R&D, clinical development, regulatory, and commercial teams to drive product delivery from concept to launch.
  • Identify and resolve executional risks to ensure timely and successful product development and rollout.
  • Engage directly and through sales/marketing teams with oncologists, NPs, practice managers, and IDNs to understand MRD use cases and pain points.
  • Engage with external BioPharma customers to navigate their MRD product needs, requirements, and workflows.
  • Define and prioritize product capabilities that align with clinical workflows and improve user experience.
  • Ensure the product aligns with physician needs and payer expectations, including actionable results and clinical utility.
  • Own the business case for the product, including pricing, COGS, and contribution to the oncology portfolio.
  • Monitor competitive activity in MRD and adjacent markets, shaping product differentiation strategy.
  • Partner with Market Access and Medical Affairs to support reimbursement and payer acceptance.
  • Collaborate with Sales and Marketing to develop positioning, messaging, and launch strategies.
  • Support development of customer-facing materials, sales training, and field enablement.
  • Contribute to publication planning and scientific communications to support the product’s value proposition.

Requirements

  • Typically requires a university degree and 15 years of related experience; or 12 years and a Master's degree; or 8 years and a PhD; or 5 years and a PharmD/MD.
  • Bachelor's degree required; MBA, MPH, or advanced scientific degree preferred.
  • 8+ years of product management or commercial/medical affairs strategy experience in diagnostics, oncology, or health technology.
  • Demonstrated success in launching and scaling healthcare products in the oncology or molecular diagnostics space.
  • Deep understanding of MRD, liquid biopsy, or cancer surveillance markets.
  • Strong working knowledge of patient and oncologist journey/touch points in the MRD space.
  • Comprehensive knowledge of MRD competitive landscape, offerings, and reimbursement strategies.
  • Strong strategic thinking, execution rigor, and cross-functional leadership skills.
  • Prior experience with product development, lifecycle management, and product launch.
  • Commercial awareness including market access, evidence generation, and provider adoption drivers.

Nice to Have

  • Experience with product development, lifecycle management, and product launch in healthcare diagnostics.
  • Knowledge of reimbursement landscape and evidence strategies for oncology diagnostics.

Qualifications

  • Bachelor's degree required.
  • Advanced degrees (MBA, MPH, PhD, PharmD/MD) preferred.
  • Minimum 8 years of relevant experience in product management or related fields.

Benefits & Perks

  • Hybrid work model with scheduled in-office days and work-from-home flexibility.
  • Pay transparency with salary range for Palo Alto or Redwood City, CA: $182,700 to $251,250, excluding benefits, bonus, or equity.
  • Support for reasonable accommodations during hiring process.

Working at Guardant Health

Guardant Health is committed to diversity and inclusion, providing reasonable accommodations for candidates with disabilities or other needs. The company emphasizes collaboration, innovation, and advancing science for patient benefit, fostering a flexible work environment that balances work-life integration.

Apply Now

Job Details

Posted AtJun 27, 2025
Job CategoryProduct Management
Salary183k-251k
Job TypeFull Time
Work ModeHybrid
ExperienceDirector

Job Skills

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About Guardant Health

Website

guardanthealth.com

Company Size

1001-5000 employees

Location

Palo Alto, CA

Industry

Medical and Diagnostic Laboratories

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